Keiichi Mitsuyama Selected Research

sodium sulfate (sodium bisulfate)

1/2020	Topical Therapy with Antisense Tumor Necrosis Factor Alpha Using Novel β-Glucan-Based Drug Delivery System Ameliorates Intestinal Inflammation.
1/2011	New prebiotics from rice bran ameliorate inflammation in murine colitis models through the modulation of intestinal homeostasis and the mucosal immune system.
2/2010	Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
2/2006	Eubacterium limosum ameliorates experimental colitis and metabolite of microbe attenuates colonic inflammatory action with increase of mucosal integrity.
1/2002	Prebiotic treatment of experimental colitis with germinated barley foodstuff: a comparison with probiotic or antibiotic treatment.

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Keiichi Mitsuyama Research Topics

Disease

39	Ulcerative Colitis 11/2022 - 01/2002
23	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 07/2023 - 05/2005
22	Colitis 07/2023 - 01/2002
16	Crohn Disease (Crohn's Disease) 11/2022 - 01/2006
12	Inflammation (Inflammations) 01/2020 - 01/2002
9	Neoplasms (Cancer) 07/2023 - 02/2010
5	Body Weight (Weight, Body) 01/2011 - 01/2003
4	Liver Cirrhosis (Hepatic Cirrhosis) 08/2022 - 11/2009
3	Intestinal Diseases (Diseases, Intestinal) 05/2020 - 04/2014
3	Colonic Neoplasms (Colon Cancer) 04/2013 - 10/2008
3	Colorectal Neoplasms (Colorectal Cancer) 07/2011 - 01/2006
2	Pouchitis 11/2022 - 01/2008
2	Varicose Veins (Varicose Vein) 08/2022 - 05/2012
2	Fibrosis (Cirrhosis) 08/2022 - 01/2022
2	Portal Hypertension 08/2022 - 01/2014
2	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 01/2022 - 03/2018
2	Autoimmune Hepatitis 01/2022 - 10/2018
2	Ulcer 09/2021 - 03/2014
2	Pain (Aches) 10/2020 - 07/2020
2	Abdominal Pain (Pain, Abdominal) 10/2015 - 04/2010
2	Malnutrition (Nutritional Deficiencies) 11/2009 - 11/2009
2	Carcinogenesis 01/2009 - 10/2008
1	Disease Progression 01/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Wounds and Injuries (Trauma) 09/2021
1	COVID-19 11/2020
1	Pediatric Crohn's disease 05/2020
1	Jaundice (Icterus) 10/2018
1	Lung Neoplasms (Lung Cancer) 08/2018

Drug/Important Bio-Agent (IBA)

13	CytokinesIBA 09/2021 - 06/2004
11	PrebioticsIBA 10/2013 - 01/2002
9	Dextran SulfateIBA 11/2020 - 01/2003
8	Therapeutic UsesIBA 04/2013 - 01/2002
7	EnzymesIBA 03/2018 - 01/2006
7	Proteins (Proteins, Gene)FDA Link 06/2013 - 02/2002
5	AntibodiesIBA 07/2023 - 06/2004
5	SteroidsIBA 01/2021 - 04/2011
5	Dextrans (Dextran)FDA Link 01/2020 - 01/2002
5	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2020 - 01/2002
5	Interleukin-6 (Interleukin 6)IBA 02/2010 - 01/2003
4	Leukocyte L1 Antigen Complex (Calgranulin)IBA 07/2023 - 01/2018
4	Peptides (Polypeptides)IBA 09/2021 - 01/2005
4	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020 - 12/2004
4	ImmunosorbentsIBA 01/2018 - 01/2006
4	Butyrates (Butyrate)IBA 01/2011 - 01/2002
3	Glycoproteins (Glycoprotein)IBA 07/2023 - 05/2020
3	AdrenomedullinIBA 11/2022 - 09/2016
3	Myeloblastin (Proteinase 3)IBA 01/2022 - 03/2018
3	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2022 - 03/2018
3	AcidsIBA 09/2021 - 02/2006
3	Macrophage Migration-Inhibitory FactorsIBA 06/2012 - 01/2008
3	Volatile Fatty AcidsIBA 07/2011 - 01/2003
3	Glutamine (L-Glutamine)FDA Link 11/2003 - 01/2003
2	Immune Checkpoint InhibitorsIBA 07/2023 - 08/2018
2	Leucine (L-Leucine)FDA Link 07/2023 - 01/2021
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 01/2021
2	SolutionsIBA 09/2021 - 01/2008
2	CurcuminIBA 12/2020 - 12/2006
2	Indigo Carmine (Indigo Blue)IBA 02/2020 - 01/2018
2	Immunoglobulins (Immunoglobulin)IBA 10/2018 - 02/2012
2	theasinensin AIBA 06/2018 - 09/2011
2	Interleukin-10 (Interleukin 10)IBA 01/2016 - 01/2006
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2015 - 02/2002
2	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 12/2011 - 04/2009
2	AzoxymethaneIBA 07/2011 - 10/2008
2	Interferon-gamma (Interferon, gamma)IBA 01/2011 - 01/2008
2	Serotonin (5 Hydroxytryptamine)IBA 01/2011 - 04/2010
2	Branched-Chain Amino AcidsIBA 11/2009 - 11/2009
2	Dietary Fiber FDA Link 11/2003 - 01/2003
1	Collagen Type IV (Type IV Collagen)IBA 08/2022
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 08/2022
1	Serum AlbuminIBA 08/2022
1	Alanine Transaminase (SGPT)IBA 08/2022
1	Antiviral Agents (Antivirals)IBA 08/2022
1	Growth Differentiation Factor 15IBA 01/2022
1	Ethanol (Ethyl Alcohol)IBA 09/2021
1	HydrogelsIBA 09/2021
1	RADA16-IIBA 09/2021
1	CollagenIBA 09/2021
1	Peroxidase (Myeloperoxidase)IBA 06/2021
1	DefensinsIBA 12/2020
1	Interleukin-22 (IL-22)IBA 12/2020
1	Angiotensin-Converting Enzyme 2IBA 11/2020
1	Calcitonin Gene-Related Peptide Receptors (Calcitonin-Gene Related Peptide Receptor)IBA 11/2020
1	Transient Receptor Potential ChannelsIBA 08/2020
1	GlucansIBA 01/2020
1	Infliximab (Remicade)FDA Link 01/2019
1	Adalimumab (Humira)FDA Link 01/2019
1	Anti-Allergic Agents (Antiallergic Agents)IBA 10/2018
1	Glucose (Dextrose)FDA LinkGeneric 10/2018
1	NivolumabIBA 08/2018
1	Drinking WaterIBA 09/2017

Therapy/Procedure

21	Therapeutics 07/2023 - 12/2004
6	Blood Component Removal (Apheresis) 10/2020 - 04/2005
2	Restorative Proctocolectomy 11/2022 - 01/2008
2	Punctures 10/2020 - 07/2020
2	Colectomy 07/2020 - 10/2015
2	Oral Administration 01/2011 - 01/2002
1	Renal Dialysis (Hemodialysis) 10/2020
1	Time-to-Treatment 07/2020